Alzheimer’s starts decades before you know it – 4 warning signs your brain is in trouble

Alzheimer’s disease mostly affects people over 65, but it’s never too early to be aware of the warning signs of this common brain disorder.

And you may be able to detect them years before things go downhill.

“Alzheimer’s disease actually starts in the brain decades before you have any symptoms,” said Dr. Daniel Amen, a board-certified psychiatrist and brain imaging researcher in California, recently shared on TikTok.

Dr. Daniel Amen, a psychiatrist and brain imaging researcher, is uncovering four red flags that could signal you’re in the early stages of Alzheimer’s disease. Dr. Daniel Amen / TikTok
About 6.7 million Americans live with Alzheimer’s, which slowly erodes memory, cognitive skills and the ability to perform simple tasks. Getty Images

About 6.7 million Americans live with Alzheimer’s, which slowly erodes memory, cognitive skills and the ability to perform simple tasks.

Amen is revealing four red flags that could signal your brain is in trouble—and some risk factors you should address right away.

Poor memory

Amen said the first warning sign is that your memory is worse than it was 10 years ago.

While occasional forgetfulness is a normal part of aging, people with dementia struggle to remember recent events, conversations or key details.

The hippocampus – a region of the brain responsible for forming new memories – is one of the first areas affected by Alzheimer’s.

Poor judgment and impulsivity

Poor decision making is often an early sign of dementia. Getty Images

Damage to your frontal lobes, key areas for decision-making and reasoning, can lead to difficulty understanding risks, dealing with everyday problems and managing finances.

It is “like yours [brain] it’s going offline,” Amen explained.

Short attention span

People with Alzheimer’s may have trouble concentrating or paying attention long enough to complete tasks that were once simple.

Amen said this happens when “the anxiety — not like the ADHD you’ve had your whole life — seems to be accelerating.”

Low mood

Low mood tends to be an early sign of Alzheimer’s because the disease is affecting the areas of the brain responsible for regulating emotions. Getty Images/iStockphoto

Research has found that up to half of Alzheimer’s patients suffer depressive symptoms, which is much higher than the general population.

Patients often experience emotional changes such as irritability or severe mood swings and often have less control over their feelings because the disease is affecting the areas of the brain responsible for regulating emotions.

They may become confused or anxious about change, or about situations that take them out of their comfort zone.

Lifestyle risks

Amen also identified several behaviors that may increase the risk of dementia.

“If you have any of these risk factors, now is the time to get serious about brain health,” Amen said.

  • Obesity: “As your weight increases, the size and function of your brain decreases,” Amen explained. “That’s why I’m cut — I don’t want to intentionally do anything that damages my brain.”
  • Low energy: “Having low energy … often means lower blood flow to the brain,” Amen said.
  • Erectile dysfunction: “Because if you have blood flow problems anywhere, that means they’re everywhere,” Amen noted.
  • Chronic insomnia or sleep apnea: Sleep helps clear toxic waste from the brain.


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